Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496959 | 1.00 | CETP (0.47) | CETPMEN1KMT2APTPN1CDC25B | |
| SCHEMBL23533399 | 0.86 | CETP (0.46) | CETPMEN1KMT2APTPN1CDC25B | |
| SCHEMBL10800324 | 0.86 | CETP (0.46) | CETPMEN1KMT2ATSHRPLA2G4B | |
| SCHEMBL10764708 | 0.84 | MMP9 (0.40) | KMT2ATSHR | |
| SCHEMBL10798829 | 0.81 | CETP (0.54) | CETPMEN1KMT2APTPN1CDC25B | |
| SCHEMBL31287839 | 0.81 | CETP (0.54) | CETPMEN1KMT2APTPN1CDC25B | |
| SCHEMBL10760738 | 0.81 | CETP (0.47) | CETPMEN1KMT2APTPN1CDC25B | |
| SCHEMBL8659917 | 0.81 | CETP (0.54) | CETPMEN1KMT2APTPN1CDC25B | |
| SCHEMBL29344326 | 0.80 | TSHR (0.52) | TSHR | |
| SCHEMBL10390190 | 0.79 | CETP (0.51) | CETPMEN1KMT2APTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673672-A | ANTITUMOR AGENTS | SANDOZ PHARMACEUTICALS CORP. (US) | 1987-06-16 | — | — | US | disclosed |