Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10796133 | 0.98 | DAO (0.39) | TAAR1DAOSMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL10792771 | 0.97 | TAAR1 (0.40) | TAAR1DAOSMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL10792280 | 0.83 | SMN1; SMN2 (0.49) | TAAR1SMN1; SMN2ADORA2AADORA1ALDH1A1 | |
| SCHEMBL11276668 | 0.76 | ADRB2 (0.40) | AOC3L3MBTL1TSHR | |
| SCHEMBL10790986 | 0.76 | SLC6A2 (0.40) | TAAR1DAOSMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL30586310 | 0.76 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL10794665 | 0.75 | TAAR1 (0.37) | TAAR1DAOSMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL27716575 | 0.75 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL10790978 | 0.74 | KCNH2 (0.38) | TAAR1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL28626405 | 0.74 | SMN1; SMN2 (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32400-E | Substituted imidazole derivatives and their use as anti-thrombosis agents | FARMOS YHTYMA OY (FI) | 1987-04-14 | — | — | US | disclosed |
| US-4514412-A | HYPOTENSIVES, BETA BLOCKERS | FARMOS YHTYMA OY (FI) | 1985-04-30 | — | — | US | disclosed |
| EP-0058047-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos-Yhtyma Oy (FI) | 1984-11-07 | — | — | EP | disclosed |