Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049913 | 0.89 | CYP11B1 (0.54) | CYP11B1CYP11B2SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL10792381 | 0.84 | FNTA (0.38) | CYP11B1CYP11B2SMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL10792635 | 0.80 | CYP11B1 (0.42) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL10792243 | 0.79 | P2RX7 (0.43) | CYP11B1CYP11B2SMN1; SMN2P2RX7POLB | |
| SCHEMBL10795646 | 0.77 | SMN1; SMN2 (0.44) | CYP11B1CYP11B2SMN1; SMN2P2RX7POLB | |
| SCHEMBL1950417 | 0.76 | CYP11B1 (0.64) | CYP11B1CYP11B2SMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL10792230 | 0.76 | FNTA (0.43) | CYP11B1CYP11B2SMN1; SMN2POLBFNTA | |
| SCHEMBL10790941 | 0.75 | ACP1 (0.43) | CYP11B1CYP11B2FNTAFNTBKMT2A | |
| SCHEMBL10794794 | 0.75 | AVPR2 (0.41) | CYP11B1CYP11B2SMN1; SMN2P2RX7POLB | |
| SCHEMBL3913519 | 0.74 | SMN1; SMN2 (0.55) | CYP11B1CYP11B2SMN1; SMN2TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32400-E | Substituted imidazole derivatives and their use as anti-thrombosis agents | FARMOS YHTYMA OY (FI) | 1987-04-14 | — | — | US | disclosed |
| US-4514412-A | HYPOTENSIVES, BETA BLOCKERS | FARMOS YHTYMA OY (FI) | 1985-04-30 | — | — | US | disclosed |
| EP-0058047-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos-Yhtyma Oy (FI) | 1984-11-07 | — | — | EP | disclosed |