Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795393 | 0.95 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10797949 | 0.87 | CYP3A4 (0.49) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10795643 | 0.82 | CYSLTR2 (0.56) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10756475 | 0.81 | CYP3A4 (0.50) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10794792 | 0.78 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10794549 | 0.77 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10750507 | 0.76 | TDP1 (0.60) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10794844 | 0.75 | CYSLTR2 (0.54) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL6371432 | 0.75 | KCNH2 (0.58) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10794544 | 0.74 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207599-A1 | Arachidonic acid analogues | BEECHAM GROUP PLC (GB) | 1987-01-07 | — | — | EP | disclosed |