Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795643 | 0.87 | CYSLTR2 (0.56) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10794549 | 0.83 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10795393 | 0.82 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10794844 | 0.79 | CYSLTR2 (0.54) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10795684 | 0.78 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10795268 | 0.75 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10800365 | 0.74 | CYSLTR2 (0.49) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10753710 | 0.74 | CYP3A4 (0.55) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL28766383 | 0.74 | GPR84 (0.48) | MAPTFFAR1 | |
| SCHEMBL9659765 | 0.74 | GPR84 (0.48) | MAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207599-A1 | Arachidonic acid analogues | BEECHAM GROUP PLC (GB) | 1987-01-07 | — | — | EP | disclosed |