Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10791740 | 0.91 | HSD17B3 (0.46) | NQO1MAOAMAPTNPC1RAB9A | |
| SCHEMBL10791541 | 0.91 | HSD17B3 (0.46) | NQO1MAOAMAPTNPC1RAB9A | |
| SCHEMBL10791670 | 0.88 | HSD17B3 (0.44) | NQO1MAOAMAPTNPC1RAB9A | |
| SCHEMBL10791228 | 0.87 | MAPT (0.49) | NQO1MAOAMAPTNPC1RAB9A | |
| SCHEMBL10794643 | 0.87 | MAPT (0.52) | NQO1MAOAMAPTNPC1RAB9A | |
| SCHEMBL10791121 | 0.83 | HSD17B3 (0.48) | NQO1MAOAMAPTNPC1RAB9A | |
| SCHEMBL8588888 | 0.79 | PGAM1 (0.45) | NQO1MAOAMAPTNPC1RAB9A | |
| SCHEMBL10794993 | 0.78 | HSD17B3 (0.49) | NQO1MAOAMAPTNPC1RAB9A | |
| SCHEMBL10790913 | 0.78 | HSD17B3 (0.56) | NQO1MAOAMAPTNPC1RAB9A | |
| SCHEMBL1474617 | 0.77 | MAPT (0.52) | MAOAMAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111746-B1 | SULFONIC-ACID ESTERS OF HYDROXYCOUMARINES, THEIR PREPARATION AND MEDICINES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1987-09-16 | — | — | EP | disclosed |
| US-4618622-A | ANTIDEPRESSANTS, ANTIALLERGENS | BASF AKTIENGESELLSCHAFT (DE) | 1986-10-21 | — | — | US | disclosed |
| EP-0111746-A2 | Sulfonic-acid esters of hydroxycoumarines, their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1984-06-27 | — | — | EP | disclosed |