Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483281 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL10795980 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL9482809 | 0.92 | ALDH1A1 (0.50) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| Cefsumide SCHEMBL11217305 | 0.88 | HSD17B10 (0.75) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| Cefsumide SCHEMBL612272 | 0.88 | HSD17B10 (0.75) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| Cefsumide SCHEMBL30688405 | 0.88 | HSD17B10 (0.75) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL11652221 | 0.88 | ALDH1A1 (0.74) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL11652216 | 0.88 | ALDH1A1 (0.74) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL11655020 | 0.88 | ALDH1A1 (0.74) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL9481075 | 0.86 | PTGS1 (0.46) | ALDH1A1MAPTHSD17B10KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661590-A | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1987-04-28 | — | — | US | disclosed |
| US-4591641-A | ORAL ANTIBIOTICS; GRAM NEGATIVE AND GRAM POSITIVE BACTERIA ACTIVITY | BRISTOL-MYERS COMPANY (US) | 1986-05-27 | — | — | US | disclosed |
| US-4520022-A | BACTERIAL INFECTION IN MAMMALS | BRISTOL-MYERS COMPANY (US) | 1985-05-28 | — | — | US | disclosed |