⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25142370 | 0.73 | — | — | |
| SCHEMBL20130524 | 0.73 | — | — | |
| SCHEMBL7622236 | 0.69 | — | — | |
| SCHEMBL17148734 | 0.69 | NOS3 (0.42) | — | |
| SCHEMBL12225878 | 0.69 | — | — | |
| SCHEMBL19736771 | 0.69 | — | — | |
| SCHEMBL24914732 | 0.69 | — | — | |
| SCHEMBL16477291 | 0.69 | — | — | |
| SCHEMBL15354617 | 0.69 | — | — | |
| SCHEMBL20925205 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11679158-B2 | Biodegradable lipids for the delivery of active agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| EP-0133454-B1 | DERIVATIVES OF CARBOXYSILOXANES AND THEIR USE AS INTERNAL MOLD RELEASE AGENTS | THE DOW CHEMICAL COMPANY (US) | 1987-08-26 | — | — | EP | disclosed |
| EP-0133454-A1 | Derivatives of carboxysiloxanes and their use as internal mold release agents | THE DOW CHEMICAL COMPANY (US) | 1985-02-27 | — | — | EP | disclosed |
| US-4472341-A | REACTION INJECTION MOLDING | THE UPJOHN COMPANY (US) | 1984-09-18 | — | — | US | disclosed |