⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24565419 | 0.86 | — | — | |
| SCHEMBL21351773 | 0.80 | ADRA2A (0.41) | — | |
| SCHEMBL152241 | 0.80 | — | — | |
| SCHEMBL5696742 | 0.80 | — | — | |
| SCHEMBL466674 | 0.80 | ADRA2A (0.41) | — | |
| SCHEMBL1126029 | 0.77 | — | — | |
| SCHEMBL9752677 | 0.77 | ADRA2A (0.35) | — | |
| SCHEMBL10682497 | 0.76 | — | — | |
| SCHEMBL14738172 | 0.76 | — | — | |
| SCHEMBL4458237 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423383-A | Liquid pharmaceutical formulations of PTH conjugates | 阿森迪斯药物骨疾病股份有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-112334152-A | Initial dose of PTH conjugate | 阿森迪斯药物骨疾病股份有限公司 | 2021-02-05 | — | — | CN | claimed |
| US-10369113-B2 | Prostate specific membrane antigen (PSMA) targeted nanoparticles for therapy of prostate cancer | THE JOHNS HOPKINS UNIVERSITY (US) | 2019-08-06 | — | — | US | claimed |
| US-20170135961-A1 | PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) TARGETED NANOPARTICLES FOR THERAPY OF PROSTATE CANCER | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-05-18 | — | — | US | claimed |
| EP-2440250-A1 | TARGETED LIPOSOMES COMPRISING N-CONTAINING BISPHOSPHONATES AND USES THEREOF | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. (IL) | 2012-04-18 | — | — | EP | claimed |
| WO-2010143193-A1 | TARGETED LIPOSOMES COMPRISING N-CONTAINING BISPHOSPHONATES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2010-12-16 | — | — | WO | claimed |
| EP-2257312-A2 | NANOPARTICLES FOR TARGETED DELIVERY OF ACTIVE AGENTS TO THE LUNG | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2010-12-08 | — | — | EP | claimed |
| WO-2009121631-A2 | NANOPARTICLES FOR TARGETED DELIVERY OF ACTIVE AGENTS TO THE LUNG | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2009-10-08 | — | — | WO | claimed |
| EP-2106806-A1 | Nanoparticles for targeted delivery of active agents to the lung | Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. (DE) | 2009-10-07 | — | — | EP | claimed |
| WO-2009070302-A1 | PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) TARGETED NANOPARTICLES FOR THERAPY OF PROSTATE CANCER | THE JOHNS HOPKINS UNIVERSITY (US) | 2009-06-04 | — | — | WO | claimed |
| WO-2000043043-A1 | LIGAND-PEG POST-COATING STABILIZED LIPOPLEX AND POLYPLEX FOR TARGETED GENE DELIVERY | GEORGETOWN UNIVERSITY (US) | 2000-07-27 | — | — | WO | claimed |
| EP-0907668-A1 | AMPHIPHILIC, SEGMENTED COPOLYMER OF CONTROLLED MORPHOLOGY AND OPHTHALMIC DEVICES INCLUDING CONTACT LENSES MADE THEREFROM | Novartis AG (CH) | 1999-04-14 | — | — | EP | claimed |
| US-5807944-A | Amphiphilic, segmented copolymer of controlled morphology and ophthalmic devices including contact lenses made therefrom | CIBA VISION CORPORATION (US) | 1998-09-15 | — | — | US | claimed |
| WO-1997049740-A9 | AMPHIPHILIC, SEGMENTED COPOLYMER OF CONTROLLED MORPHOLOGY AND OPHTHALMIC DEVICES INCLUDING CONTACT LENSES MADE THEREFROM | — | 1998-04-30 | — | — | WO | claimed |
| EP-0688207-B1 | LIPID-POLYMER CONJUGATES AND LIPOSOMES | SEQUUS PHARM INC (US) | 1998-01-28 | — | — | EP | claimed |
| WO-1997049740-A1 | AMPHIPHILIC, SEGMENTED COPOLYMER OF CONTROLLED MORPHOLOGY AND OPHTHALMIC DEVICES INCLUDING CONTACT LENSES MADE THEREFROM | NOVARTIS AG (CH) | 1997-12-31 | — | — | WO | claimed |
| US-5631018-A | Lipid-polymer conjugates and liposomes | SEQUUS PHARMACEUTICALS, INC. (US) | 1997-05-20 | — | — | US | claimed |
| EP-0688207-A1 | LIPID-POLYMER CONJUGATES AND LIPOSOMES | SEQUUS PHARMACEUTICALS, INC. (US) | 1995-12-27 | — | — | EP | claimed |
| WO-1994020073-A1 | LIPID-POLYMER CONJUGATES AND LIPOSOMES | LIPOSOME TECHNOLOGY, INC. (US) | 1994-09-15 | — | — | WO | claimed |
| EP-0290109-A2 | Poly (N-acylethyleneimine)grafted polysiloxane and its preparation | Nippon Paint Co., Ltd. (JP) | 1988-11-09 | — | — | EP | claimed |