Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.43 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10796346 | 1.00 | EPHX2 (0.50) | EPHX2PPARGMAPTMAPK1MME | |
| SCHEMBL10796336 | 1.00 | EPHX2 (0.50) | EPHX2PPARGMAPTMAPK1MME | |
| SCHEMBL10389858 | 0.92 | EPHX2 (0.54) | EPHX2PPARGMAPTMAPK1PPARA | |
| SCHEMBL7362615 | 0.91 | MME (0.47) | PPARGMAPTMAPK1MMEPPARA | |
| SCHEMBL7362616 | 0.91 | MME (0.47) | PPARGMAPTMAPK1MMEPPARA | |
| SCHEMBL10793791 | 0.91 | MME (0.47) | PPARGMAPTMAPK1MMEPPARA | |
| SCHEMBL7361690 | 0.82 | CYP1A2 (0.56) | PPARGMAPTMAPK1ANPEP | |
| SCHEMBL7361695 | 0.82 | CYP1A2 (0.56) | PPARGMAPTMAPK1ANPEP | |
| SCHEMBL7361969 | 0.82 | CYP1A2 (0.56) | PPARGMAPTMAPK1ANPEP | |
| SCHEMBL7360720 | 0.80 | HRH4 (0.52) | MMEPPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |