Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 9/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345414 | 0.86 | SLC6A2 (0.58) | MTNR1BKIF11MTNR1ASLC6A4SLC6A2 | |
| SCHEMBL10345415 | 0.83 | MTNR1B (0.47) | MTNR1BKIF11MTNR1ASLC6A4SLC6A2 | |
| SCHEMBL10720684 | 0.76 | MTNR1B (0.47) | MTNR1BMTNR1ANOTUM | |
| SCHEMBL10345417 | 0.75 | MTNR1B (0.51) | MTNR1BMTNR1ATAS2R14NOTUMESR1 | |
| SCHEMBL10345842 | 0.75 | HTR2C (0.56) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL18085053 | 0.74 | SLC6A2 (0.54) | MTNR1BMTNR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL18085044 | 0.74 | SLC6A2 (0.54) | MTNR1BMTNR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10749624 | 0.71 | CYP3A4 (0.38) | KIF11 | |
| SCHEMBL7624331 | 0.70 | SLC6A2 (0.51) | MTNR1BMTNR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL18085075 | 0.69 | MTNR1B (0.44) | MTNR1BMTNR1ASLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707483-A | 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders | SMITHKLINE BECKMAN CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |