Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12226555 | 0.90 | KMT2A (0.44) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL8970364 | 0.88 | KMT2A (0.42) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL8968894 | 0.88 | KMT2A (0.42) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11038713 | 0.86 | MEN1 (0.49) | KMT2AMEN1DHODHMAPTHPGD | |
| SCHEMBL10795123 | 0.79 | MEN1 (0.49) | KMT2AMEN1MAPTIDO1HTT | |
| SCHEMBL10795158 | 0.79 | MAPT (0.62) | KMT2AMEN1MAPTHPGDHTT | |
| SCHEMBL7883074 | 0.78 | SMN1; SMN2 (0.40) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL9421891 | 0.78 | MAPT (0.52) | KMT2AMEN1CYP1A2CYP2C19EBP | |
| Tetrabuthylammonium SCHEMBL8970333 | 0.77 | L3MBTL1 (0.44) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| Tetrabuthylammonium SCHEMBL8968975 | 0.77 | L3MBTL1 (0.44) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652634-A | Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| EP-0051808-B1 | WATER-SOLUBLE MONOAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-04 | — | — | EP | disclosed |
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |
| EP-0051808-A2 | Water-soluble monoazo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-19 | — | — | EP | disclosed |