⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20425030 | 0.97 | — | — | |
| SCHEMBL24053161 | 0.82 | CYP2D6 (0.33) | — | |
| SCHEMBL23746654 | 0.80 | — | — | |
| SCHEMBL8401528 | 0.79 | — | — | |
| Trifluoroacetic Acid SCHEMBL20425222 | 0.78 | ODC1 (0.35) | — | |
| SCHEMBL7453310 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL24443914 | 0.74 | — | — | |
| SCHEMBL925414 | 0.72 | — | — | |
| SCHEMBL23957669 | 0.71 | — | — | |
| SCHEMBL1128125 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250195678-A1 | B-LYMPHOCYTE SPECIFIC AMATOXIN ANTIBODY CONJUGATES | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2025-06-19 | — | — | US | disclosed |
| US-20240409573-A1 | CALICHEAMICIN DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER INC. (US) | 2024-12-12 | — | — | US | disclosed |
| US-11993625-B2 | Calicheamicin derivatives and antibody drug conjugates thereof | PFIZER, INC. (US) | 2024-05-28 | — | — | US | disclosed |
| CN-111432844-B | PSMA-targeting amanitine conjugates | 海德堡医药研究有限责任公司 | 2023-10-27 | — | — | CN | disclosed |
| EP-3684416-B1 | PSMA-TARGETING AMANITIN CONJUGATES | HEIDELBERG PHARMA RES GMBH (DE) | 2023-03-15 | — | — | EP | disclosed |
| US-11583569-B2 | PSMA-targeting amanitin conjugates | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2023-02-21 | — | — | US | disclosed |
| US-20230024332-A1 | Antifouling Polymeric Coating Compositions | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2023-01-26 | — | — | US | disclosed |
| US-20210107909-A1 | SMALL MOLECULE MODULATORS OF PAR2 AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2021-04-15 | — | — | US | disclosed |
| US-20200370081-A1 | BIOCATALYST AND METHODS FOR SYNTHESIZING MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-11-26 | — | — | US | disclosed |
| US-20200345807-A1 | PSMA-TARGETING AMANITIN CONJUGATES | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2020-11-05 | — | — | US | disclosed |
| US-10196356-B2 | Mixed disulfide conjugates of thienopyridine compounds and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-02-05 | — | — | US | disclosed |
| US-10173980-B2 | Mixed disulfide conjugates of thienopyridine compounds and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-01-08 | — | — | US | disclosed |
| WO-2018138591-A1 | CALICHEAMICIN DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER INC. (US) | 2018-08-02 | — | — | WO | disclosed |
| US-20180155289-A1 | MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-06-07 | — | — | US | disclosed |
| EP-3305871-A1 | DEUTERATED CARBAZOLE AND ITS USE IN ORGANIC ELECTROLUMINESCENT DEVICES | UDC Ireland Limited (IE) | 2018-04-11 | — | — | EP | disclosed |
| US-20170334853-A1 | MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-11-23 | — | — | US | disclosed |
| US-9776982-B2 | Treprostinil derivative compounds and methods of using same | Corsair Pharma, Inc. (US) | 2017-10-03 | — | — | US | disclosed |
| CN-104870480-B | Method for diene elastomer free radical grafting | 米其林集团总公司 | 2016-12-21 | — | — | CN | disclosed |
| US-20150299367-A1 | PROCESS FOR RADICAL GRAFTING OF A DIENE ELASTOMER | MICHELIN RECHERCHE ET TECHNIQUE, S.A. (CH) | 2015-10-22 | — | — | US | disclosed |
| US-4668669-A | BACTERICIDES, MICROBIOCIDES, SYNERGISTINS | RHONE-POULENC SANTE (FR) | 1987-05-26 | — | — | US | disclosed |