Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL9725377 | 1.00 | MEN1 (0.41) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL28856691 | 1.00 | MEN1 (0.41) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL2673731 | 1.00 | MEN1 (0.41) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL11672030 | 0.98 | MEN1 (0.40) | MEN1KMT2AATMHTR2ACSNK1E | |
| SCHEMBL14768367 | 0.85 | MEN1 (0.42) | MEN1KMT2AATMHTR2ACSNK1E | |
| SCHEMBL27886667 | 0.85 | MEN1 (0.42) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL9725408 | 0.84 | MEN1 (0.40) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL10803745 | 0.84 | MEN1 (0.40) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL9725371 | 0.84 | MEN1 (0.40) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL10797578 | 0.84 | MEN1 (0.40) | MEN1KMT2AATMHTR2ACSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4640786-A | HIGH TEMPERATURES | THE DOW CHEMICAL COMPANY (US) | 1987-02-03 | — | — | US | disclosed |
| EP-0139260-A1 | Phosphonium salt corrosion inhibitors for high density brines | THE DOW CHEMICAL COMPANY (US) | 1985-05-02 | — | — | EP | disclosed |