Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL9725371 | 1.00 | MEN1 (0.40) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL10797578 | 1.00 | MEN1 (0.40) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL10803745 | 1.00 | MEN1 (0.40) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL10803277 | 1.00 | MEN1 (0.40) | MEN1KMT2AATMHTR2ACSNK1E | |
| SCHEMBL28977285 | 0.85 | AOC3 (0.39) | MEN1KMT2AATMHTR2A | |
| Phosphine SCHEMBL2673731 | 0.84 | MEN1 (0.41) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL28856691 | 0.84 | MEN1 (0.41) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL9725377 | 0.84 | MEN1 (0.41) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL10797446 | 0.84 | MEN1 (0.41) | MEN1KMT2AATMHTR2ACSNK1E | |
| Phosphine SCHEMBL11672030 | 0.82 | MEN1 (0.40) | MEN1KMT2AATMHTR2ACSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3435766-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION | Dentsply Sirona Inc. (US) | 2019-02-06 | — | — | EP | claimed |
| WO-2017173294-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION | DENTSPLY SIRONA INC. (US) | 2017-10-05 | — | — | WO | claimed |
| US-20170280725-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION | DENTSPLY SIRONA INC (US) | 2017-10-05 | — | — | US | claimed |
| US-20230022721-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION | DENTSPLY SIRONA INC. (US) | 2023-01-26 | — | — | US | disclosed |
| EP-3435766-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION | Dentsply Sirona Inc. (US) | 2019-02-06 | — | — | EP | disclosed |
| US-20170280725-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION | DENTSPLY SIRONA INC (US) | 2017-10-05 | — | — | US | disclosed |
| WO-2017173294-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION | DENTSPLY SIRONA INC. (US) | 2017-10-05 | — | — | WO | disclosed |
| US-5102874-A | Synergistic | ECOLAB INC. (US) | 1992-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170280725-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION | FGB, TFPI, F12 | MEN1 3757/4885KMT2A 4151/4885ATM 4114/4885 |
| US-20230022721-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION | FGB, TFPI, F12 | MEN1 3757/4885KMT2A 4151/4885ATM 4114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.