Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10793642 | 1.00 | TSHR (0.40) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9821415 | 0.93 | TSHR (0.43) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11074263 | 0.89 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10794969 | 0.89 | TSHR (0.39) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11072728 | 0.89 | TSHR (0.39) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10793668 | 0.88 | TSHR (0.43) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9576597 | 0.88 | TSHR (0.43) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10115076 | 0.88 | TSHR (0.45) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9576545 | 0.87 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9576331 | 0.87 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463149-A | UNSATURATED POLYSILOXANES | POLYMER TECHNOLOGY CORPORATION (US) | 1984-07-31 | — | — | US | claimed |
| EP-0211067-A1 | OXYGEN-PERMEABLE LENSES. | BAUSCH & LOMB (US) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986004342-A1 | OXYGEN-PERMEABLE LENSES | BAUSCH AND LOMB INCORPORATED (US) | 1986-07-31 | — | — | WO | disclosed |
| US-4463149-A | UNSATURATED POLYSILOXANES | POLYMER TECHNOLOGY CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |