Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10798024 | 0.89 | TSHR (0.40) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10793642 | 0.89 | TSHR (0.40) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9576291 | 0.85 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12870020 | 0.85 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL30825544 | 0.85 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9821415 | 0.84 | TSHR (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11073250 | 0.84 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10115076 | 0.84 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11075328 | 0.84 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9576342 | 0.84 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463149-A | UNSATURATED POLYSILOXANES | POLYMER TECHNOLOGY CORPORATION (US) | 1984-07-31 | — | — | US | claimed |
| US-4463149-A | UNSATURATED POLYSILOXANES | POLYMER TECHNOLOGY CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |