Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.56 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12952546 | 0.92 | ANPEP (0.46) | ANPEPERAP2SPHK1ALDH1A1TSHR | |
| SCHEMBL405537 | 0.83 | ANPEP (0.59) | ANPEPERAP2SPHK1ALDH1A1TSHR | |
| SCHEMBL11801411 | 0.82 | ANPEP (0.53) | ANPEPERAP2SPHK1ALDH1A1TSHR | |
| SCHEMBL11791450 | 0.82 | ANPEP (0.53) | ANPEPERAP2SPHK1ALDH1A1TSHR | |
| SCHEMBL1460194 | 0.82 | ANPEP (0.53) | ANPEPERAP2ALDH1A1TSHRS1PR2 | |
| SCHEMBL24660875 | 0.81 | PKM (0.35) | ANPEPERAP2SPHK1POLB | |
| SCHEMBL29153566 | 0.79 | ANPEP (0.58) | ANPEPERAP2ALDH1A1TSHRS1PR2 | |
| SCHEMBL29153553 | 0.79 | ANPEP (0.58) | ANPEPERAP2ALDH1A1TSHRS1PR2 | |
| SCHEMBL2781205 | 0.79 | ANPEP (0.33) | ANPEPERAP2SPHK1 | |
| SCHEMBL1459388 | 0.78 | ANPEP (0.50) | ANPEPERAP2SPHK1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147279-B1 | PROCESS FOR THE PREPARATION OF DIAMINO-ALCOHOLS | Laboratoires Pharmascience (FR) | 1987-03-04 | — | — | EP | disclosed |
| EP-0147279-A2 | Process for the preparation of diamino-alcohols | Laboratoires Pharmascience (FR) | 1985-07-03 | — | — | EP | disclosed |