SCHEMBL10798698

SCHEMBL10798698

CCCC(CCOS(C)(=O)=O)OS(C)(=O)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
LMNA P02545 1/20 0.43
MMP9 P14780 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA12 O43570 1/20 0.34
CA7 P43166 1/20 0.34
CA14 Q9ULX7 1/20 0.34
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32
HDAC8 Q9BY41 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4305884 0.92 ALDH1A1 (0.50) ALDH1A1KDM4EUSP2LMNAMMP9
SCHEMBL4998468 0.87 ALDH1A1 (0.43) ALDH1A1KDM4EUSP2LMNAMMP9
SCHEMBL9677047 0.87 TSHR (0.43) ALDH1A1KDM4EUSP2LMNAMMP9
SCHEMBL25760269 0.86 ALDH1A1 (0.44) ALDH1A1KDM4EUSP2LMNAMMP9
SCHEMBL6666191 0.82 ALDH1A1 (0.44) ALDH1A1KDM4EUSP2LMNAMMP9
SCHEMBL10431120 0.82 CA12 (0.39) ALDH1A1KDM4EUSP2LMNAMMP9
SCHEMBL776817 0.82 ALDH1A1 (0.44) ALDH1A1KDM4EUSP2LMNAMMP9
SCHEMBL9291019 0.80 ALDH1A1 (0.43) ALDH1A1KDM4EUSP2LMNAMMP9
SCHEMBL9291014 0.80 ALDH1A1 (0.43) ALDH1A1KDM4EUSP2LMNAMMP9
SCHEMBL13636610 0.79 ALDH1A1 (0.40) ALDH1A1CA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4684396-A Triazole and imidazole compounds useful as plant growth regulators and fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-08-04 US disclosed
EP-0153797-A1 Heterocyclic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-09-04 EP disclosed