Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10794158 | 0.78 | DPP4 (0.38) | LMNATSHR | |
| SCHEMBL3667462 | 0.67 | TSHR (0.50) | ALDH1A1TSHRHPGDCA1CA2 | |
| SCHEMBL2120702 | 0.66 | TSHR (0.55) | ALDH1A1TSHRCHRNA7CA1CA2 | |
| SCHEMBL11289948 | 0.65 | CHRNA7 (0.42) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL1409623 | 0.64 | TSHR (0.60) | ALDH1A1TSHRMEN1KMT2ACA1 | |
| SCHEMBL6049865 | 0.63 | TSHR (0.58) | LMNAALDH1A1TSHRHPGDCA1 | |
| Iodide SCHEMBL25233686 | 0.62 | TSHR (0.57) | ALDH1A1TSHRMEN1KMT2ACA1 | |
| SCHEMBL6403156 | 0.62 | ACHE (0.44) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL16447038 | 0.62 | TSHR (0.57) | ALDH1A1TSHRMEN1KMT2ACA1 | |
| SCHEMBL3676489 | 0.62 | TSHR (0.44) | TSHRHPGDCA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088667-B1 | HALOGENATED AROMATIC DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF POLYURETHANES | ELF ATOCHEM S.A. (FR) | 1987-04-08 | — | — | EP | claimed |