Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 10/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10798791 | 0.86 | CYSLTR1 (0.36) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL10803802 | 0.85 | CYSLTR2 (0.35) | HPGDCYSLTR1CYSLTR2 | |
| SCHEMBL10974390 | 0.84 | CYSLTR1 (0.35) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL10798804 | 0.82 | CYSLTR1 (0.35) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL10726796 | 0.81 | CYSLTR1 (0.53) | GRM2CYSLTR1KMT2ACYSLTR2 | |
| SCHEMBL10799377 | 0.75 | CYSLTR1 (0.39) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL10798690 | 0.75 | CYSLTR1 (0.39) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL10798437 | 0.74 | CYSLTR1 (0.38) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL10799118 | 0.72 | CYSLTR2 (0.38) | CYSLTR1CYSLTR2 | |
| SCHEMBL10804350 | 0.71 | CYSLTR2 (0.35) | ALDH1A1HPGDCYSLTR1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132124-B1 | NOVEL PHARMACEUTICAL COMPOUNDS AND THEIR PREPARATION | Lilly Industries Limited (GB) | 1987-09-23 | — | — | EP | disclosed |
| EP-0132124-A1 | Novel pharmaceutical compounds and their preparation | Lilly Industries Limited (GB) | 1985-01-23 | — | — | EP | disclosed |