Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 8/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.36 |
| ▸ | MMP2 | P08253 | 6/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268639 | 0.82 | ACE (0.51) | ACE | |
| SCHEMBL11268645 | 0.82 | ACE (0.51) | ACE | |
| SCHEMBL11214390 | 0.81 | ACE (0.38) | ACE | |
| SCHEMBL11214388 | 0.81 | ACE (0.38) | ACE | |
| SCHEMBL25367563 | 0.79 | MMP2 (0.39) | MMP2ANPEP | |
| SCHEMBL25367568 | 0.79 | MMP2 (0.39) | MMP2ANPEP | |
| SCHEMBL10795543 | 0.78 | MMP2 (0.34) | ACEMMP2ANPEP | |
| SCHEMBL11258866 | 0.78 | ACE (0.39) | ACEMMP2 | |
| SCHEMBL11258881 | 0.78 | ACE (0.39) | ACEMMP2 | |
| SCHEMBL15586366 | 0.77 | MMP2 (0.38) | DPP4DPP8DPP9MMP2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4684660-A | Mercaptoacyldepeptides | E. R. SQUIBB & SONS, INC. (US) | 1987-08-04 | — | — | US | disclosed |