Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10798170 | 0.93 | CYP3A4 (0.63) | CYP3A4KDM4EMAPTCYP2C9CYP2C19 | |
| SCHEMBL6371432 | 0.91 | KCNH2 (0.58) | CYP3A4KDM4EMAPTCYP2C9CYP2C19 | |
| SCHEMBL31544587 | 0.83 | KCNH2 (0.54) | CYP3A4KDM4EMAPTCYP2C9CYP2C19 | |
| SCHEMBL4280713 | 0.83 | KCNH2 (0.54) | CYP3A4KDM4EMAPTCYP2C9CYP2C19 | |
| SCHEMBL10812341 | 0.83 | KCNH2 (0.50) | CYP3A4KDM4EMAPTCYP2C9CYP2C19 | |
| SCHEMBL10437178 | 0.81 | CYSLTR2 (0.49) | CYP3A4KDM4EMAPTCYP2C9CYP2C19 | |
| SCHEMBL10437177 | 0.81 | CYSLTR2 (0.49) | CYP3A4KDM4EMAPTCYP2C9CYP2C19 | |
| SCHEMBL10437174 | 0.81 | CYSLTR2 (0.49) | CYP3A4KDM4EMAPTCYP2C9CYP2C19 | |
| SCHEMBL10795247 | 0.81 | CYSLTR2 (0.65) | CYP3A4KDM4EMAPTCYP2C9CYP2C19 | |
| SCHEMBL28622511 | 0.81 | KCNH2 (0.47) | CYP3A4KDM4EMAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207599-A1 | Arachidonic acid analogues | BEECHAM GROUP PLC (GB) | 1987-01-07 | — | — | EP | disclosed |