Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799449 | 0.86 | TDP1 (0.60) | TDP1TRPV1EPHX2MEN1KMT2A | |
| SCHEMBL7108246 | 0.86 | MEN1 (0.53) | TDP1TRPV1EPHX2TLR8TLR7 | |
| SCHEMBL10799599 | 0.85 | KDM4E (0.56) | TDP1TRPV1EPHX2MEN1KMT2A | |
| SCHEMBL10796005 | 0.85 | TDP1 (0.61) | TDP1TRPV1EPHX2TLR8TLR7 | |
| SCHEMBL10707659 | 0.83 | MEN1 (0.50) | TDP1TRPV1EPHX2TLR8TLR7 | |
| SCHEMBL11552769 | 0.79 | TRPV1 (0.48) | TDP1TRPV1EPHX2MEN1KMT2A | |
| SCHEMBL10871199 | 0.78 | MEN1 (0.64) | TDP1TRPV1EPHX2TLR8TLR7 | |
| SCHEMBL11557740 | 0.78 | TDP1 (0.53) | TDP1TRPV1EPHX2MEN1KMT2A | |
| SCHEMBL11026869 | 0.78 | MEN1 (0.53) | TDP1TRPV1EPHX2TLR8TLR7 | |
| SCHEMBL10795624 | 0.78 | TDP1 (0.61) | TDP1TRPV1EPHX2TLR8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32418-E | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1987-05-12 | — | — | US | claimed |
| US-4170657-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1979-10-09 | — | — | US | claimed |
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |