Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707659 | 0.96 | MEN1 (0.50) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL11026869 | 0.91 | MEN1 (0.53) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL10871199 | 0.91 | MEN1 (0.64) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL10795425 | 0.90 | TDP1 (0.51) | MEN1KMT2AMAPTUSP2ALOX15 | |
| Diftrifmeouron SCHEMBL7104017 | 0.90 | EPHX2 (0.63) | MEN1KMT2AMAPTTDP1TRPV1 | |
| SCHEMBL9651342 | 0.89 | MEN1 (0.48) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL11552769 | 0.88 | TRPV1 (0.48) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL9635433 | 0.87 | MEN1 (0.52) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL10786095 | 0.87 | MEN1 (0.43) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL9651658 | 0.87 | MEN1 (0.47) | MEN1KMT2AMAPTUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32418-E | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1987-05-12 | — | — | US | claimed |
| US-4170657-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1979-10-09 | — | — | US | claimed |
| US-4089975-A | DIPHENYL ACYLUREA DERIVATIVE | THE DOW CHEMICAL COMPANY (US) | 1978-05-16 | — | — | US | claimed |
| EP-0917822-B1 | Method to control animal ecto-parasites | SUMITOMO CHEMICAL CO (JP) | 2003-10-08 | — | — | EP | disclosed |
| US-6333355-B2 | 1-(2,6-DIFLUOROBENZOYL)-3-(2-FLUORO-4-(1,1,2,3,3,3 -HEXAFLUOROP ROPOXY)PHENYL)UREA; FLEAS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-12-25 | — | — | US | disclosed |
| US-20010044470-A1 | METHOD TO CONTROL ANIMAL ECTO-PARASITES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-22 | — | — | US | disclosed |
| EP-0917822-A1 | Method to control animal ecto-parasites | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |
| US-4089975-A | DIPHENYL ACYLUREA DERIVATIVE | THE DOW CHEMICAL COMPANY (US) | 1978-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044470-A1 | METHOD TO CONTROL ANIMAL ECTO-PARASITES | ENPP3, ENPP1, TUBA3C | MEN1 3311/4885KMT2A 1802/4885MAPT 4466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.