Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | EGFR | P00533 | 9/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11592831 | 0.88 | MEN1 (0.54) | MEN1KMT2AHSP90AA1MAPTEGFR | |
| SCHEMBL11741296 | 0.87 | KMT2A (0.65) | MEN1KMT2AHSP90AA1MAPTEGFR | |
| SCHEMBL10796883 | 0.86 | MEN1 (0.54) | MEN1KMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL10796503 | 0.86 | MEN1 (0.54) | MEN1KMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL10797256 | 0.86 | KMT2A (0.64) | MEN1KMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL10801009 | 0.83 | KIF11 (0.58) | MEN1KMT2AHSP90AA1MAPTEGFR | |
| SCHEMBL10796852 | 0.82 | EGFR (0.48) | MEN1KMT2AHSP90AA1MAPTEGFR | |
| SCHEMBL10484818 | 0.82 | KMT2A (0.52) | MEN1KMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL10797198 | 0.82 | KMT2A (0.51) | MEN1KMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL10799925 | 0.79 | TYMS (0.46) | MEN1KMT2AHSP90AA1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670596-A | INSECTICIDE, MITICIDE | ELI LILLY AND COMPANY (US) | 1987-06-02 | — | — | US | disclosed |