Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799286 | 0.93 | GPR84 (0.34) | CYSLTR1CYSLTR2GPR84BCHECTSD | |
| SCHEMBL10798392 | 0.85 | CYSLTR1 (0.33) | CYSLTR1CYSLTR2GPR84ESR1ADRA2A | |
| SCHEMBL10975508 | 0.84 | ESR1 (0.35) | CYSLTR1CYSLTR2GPR84ESR1ADRA2A | |
| SCHEMBL10804059 | 0.83 | CYSLTR1 (0.34) | CYSLTR1CYSLTR2GPR84BCHECTSD | |
| SCHEMBL10799322 | 0.82 | MEN1 (0.36) | CYSLTR1CYSLTR2GPR84ESR1ADRA2A | |
| SCHEMBL10727409 | 0.76 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2LMNACTSDGRM2 | |
| SCHEMBL10798437 | 0.76 | CYSLTR1 (0.38) | CYSLTR1CYSLTR2GPR84CTSDGRM2 | |
| SCHEMBL10799377 | 0.73 | CYSLTR1 (0.39) | CYSLTR1CYSLTR2GPR84CTSDGRM2 | |
| SCHEMBL10798804 | 0.73 | CYSLTR1 (0.35) | CYSLTR1CYSLTR2GPR84GRM2 | |
| SCHEMBL11393475 | 0.72 | PPARG (0.36) | CYSLTR1CYSLTR2LMNAHSD17B10GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132124-B1 | NOVEL PHARMACEUTICAL COMPOUNDS AND THEIR PREPARATION | Lilly Industries Limited (GB) | 1987-09-23 | — | — | EP | disclosed |
| EP-0132124-A1 | Novel pharmaceutical compounds and their preparation | Lilly Industries Limited (GB) | 1985-01-23 | — | — | EP | disclosed |