Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 16/20 | 0.86 |
| ▸ | CTSS | P25774 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10801167 | 0.96 | KCNK3 (0.81) | KCNK3CTSS | |
| SCHEMBL10800573 | 0.96 | KCNK3 (0.80) | KCNK3CTSS | |
| SCHEMBL14784434 | 0.95 | KCNK3 (0.80) | KCNK3 | |
| SCHEMBL10803398 | 0.93 | KCNK3 (0.76) | KCNK3CTSS | |
| SCHEMBL14784886 | 0.93 | KCNK3 (1.00) | KCNK3 | |
| SCHEMBL10805959 | 0.92 | KCNK3 (0.88) | KCNK3CTSS | |
| SCHEMBL10804033 | 0.92 | KCNK3 (0.75) | KCNK3CTSS | |
| SCHEMBL10800484 | 0.91 | KCNK3 (0.74) | KCNK3CTSS | |
| SCHEMBL14783923 | 0.91 | KCNK3 (1.00) | KCNK3CTSS | |
| SCHEMBL14791429 | 0.88 | KCNK3 (1.00) | KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086422-B1 | PHARMACOLOGICALLY ACTIVE PYRAZOLO(4,3-C)PYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1987-09-30 | — | — | EP | disclosed |