Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 17/20 | 0.76 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10801107 | 0.93 | KCNK3 (0.86) | KCNK3CTSS | |
| SCHEMBL10804033 | 0.91 | KCNK3 (0.75) | KCNK3CTSS | |
| SCHEMBL10801167 | 0.89 | KCNK3 (0.81) | KCNK3CTSS | |
| SCHEMBL10800573 | 0.89 | KCNK3 (0.80) | KCNK3CTSS | |
| SCHEMBL14784434 | 0.88 | KCNK3 (0.80) | KCNK3 | |
| SCHEMBL14784886 | 0.86 | KCNK3 (1.00) | KCNK3 | |
| SCHEMBL14784680 | 0.86 | KCNK3 (1.00) | KCNK3 | |
| SCHEMBL10805959 | 0.86 | KCNK3 (0.88) | KCNK3CTSS | |
| SCHEMBL10805596 | 0.85 | KCNK3 (0.65) | KCNK3 | |
| SCHEMBL10800484 | 0.85 | KCNK3 (0.74) | KCNK3CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086422-B1 | PHARMACOLOGICALLY ACTIVE PYRAZOLO(4,3-C)PYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1987-09-30 | — | — | EP | disclosed |
| EP-0086422-A2 | Pharmacologically active pyrazolo(4,3-c)pyridines | GRUPPO LEPETIT S.p.A. (IT) | 1983-08-24 | — | — | EP | disclosed |