Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15471245 | 0.92 | CA1 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL15473887 | 0.85 | CA1 (0.48) | CA1CA2CA7CA9CA12 | |
| SCHEMBL21659609 | 0.83 | CA1 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL29675910 | 0.81 | KMT2A (0.49) | GAAALDH1A1APLNRMAPK1L3MBTL1 | |
| SCHEMBL29771456 | 0.79 | CA2 (0.57) | CA1CA2CA7CA9CA12 | |
| SCHEMBL8784464 | 0.79 | CA1 (0.57) | CA1CA2CA7CA9CA12 | |
| SCHEMBL30948566 | 0.79 | CA1 (0.57) | CA1CA2CA7CA9CA12 | |
| SCHEMBL9326106 | 0.79 | CA1 (0.57) | CA1CA2CA7CA9CA12 | |
| SCHEMBL19468259 | 0.79 | CA1 (0.57) | CA1CA2CA7CA9CA12 | |
| SCHEMBL142899 | 0.79 | CA2 (0.57) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124232-B1 | ANTIBIOTICS AND THEIR PREPARATION | THE UPJOHN COMPANY (US) | 1987-07-15 | — | — | EP | disclosed |
| US-4505895-A | Antibiotic 273a1 | THE UPJOHN COMPANY (US) | 1985-03-19 | — | — | US | disclosed |