SCHEMBL10801464

SCHEMBL10801464

NC1=CC(=Nc2ccc(O)cc2Cl)C(OCCO)=CC1=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.32
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10801997 0.81 MEN1 (0.35) BACE1
SCHEMBL11315992 0.78 CA12 (0.33) BACE1
SCHEMBL10796505 0.71 CYP3A4 (0.32) PTPN1
SCHEMBL15018445 0.69 BACE1 (0.34) BACE1
SCHEMBL15018013 0.69 LTA4H (0.33) BACE1
SCHEMBL15018443 0.69 BACE1 (0.34) BACE1
SCHEMBL15018011 0.69 LTA4H (0.33) BACE1
SCHEMBL15037508 0.68 NR5A1 (0.37) BACE1
SCHEMBL20853562 0.68 NR5A1 (0.37) BACE1
SCHEMBL11626956 0.67 KMT2A (0.40) BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4702863-A Indoaniline and indophenol compounds, a process for their preparation, dyeing compositions containing them and a hair-dyeing process L'OREAL (FR) 1987-10-27 US disclosed