Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013617 | 0.81 | MCL1 (0.41) | MCL1 | |
| SCHEMBL133731 | 0.75 | — | — | |
| SCHEMBL5463212 | 0.73 | MCL1 (0.42) | MCL1ALDH1A1MAPTKMT2A | |
| SCHEMBL1011084 | 0.73 | — | — | |
| SCHEMBL10769371 | 0.71 | — | — | |
| SCHEMBL27987112 | 0.71 | — | — | |
| SCHEMBL1012319 | 0.71 | — | — | |
| SCHEMBL15571415 | 0.70 | MCL1 (0.39) | MCL1ALDH1A1 | |
| SCHEMBL769718 | 0.70 | MCL1 (0.39) | MCL1 | |
| SCHEMBL18213897 | 0.70 | CES1 (0.38) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790209-B2 | Kinase inhibitors | RESPIVERT LIMITED (GB) | 2017-10-17 | — | — | US | disclosed |
| US-20160340343-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2016-11-24 | — | — | US | disclosed |
| US-20150225373-A1 | KINASE INHIBITORS | TOPIVERT PHARMA LIMITED (GB) | 2015-08-13 | — | — | US | disclosed |
| EP-0129928-B1 | OXAZOLYL-SUBSTITUTED DIAZAHETEROCYCLES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-09-02 | — | — | EP | disclosed |
| US-4500345-A | IOSTEMERGENCE AND PREEMERGENCE HERBICIDES | SHELL OIL COMPANY (US) | 1985-02-19 | — | — | US | disclosed |
| US-4493728-A | HERBICIDES | SHELL OIL COMPANY (US) | 1985-01-15 | — | — | US | disclosed |
| EP-0129928-A1 | Oxazolyl-substituted diazaheterocycles | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1985-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225373-A1 | KINASE INHIBITORS | SYK, SRC, BTK | MCL1 2082/4885MEN1 4160/4885ALDH1A1 2504/4885 |
| US-20160340343-A1 | KINASE INHIBITORS | SYK, LYN, BTK | MCL1 2009/4885MEN1 4438/4885ALDH1A1 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.