Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | RECQL | P46063 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | BLM | P54132 | 4/20 | 0.61 |
| ▸ | APEX1 | P27695 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | MTOR | P42345 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10924534 | 0.98 | TDP1 (0.72) | TDP1KDM4EMAPK1RECQLMAPT | |
| Ethylnorepinephrine SCHEMBL249736 | 0.83 | TDP1 (0.96) | TDP1KDM4EMAPK1RECQLMAPT | |
| Ethylnorepinephrine SCHEMBL29711047 | 0.83 | TDP1 (0.96) | TDP1KDM4EMAPK1RECQLMAPT | |
| Ethylnorepinephrine SCHEMBL521301 | 0.81 | KDM4E (1.00) | TDP1KDM4EMAPK1RECQLMAPT | |
| Ethylnorepinephrine SCHEMBL75742 | 0.81 | KDM4E (1.00) | TDP1KDM4EMAPK1RECQLMAPT | |
| SCHEMBL26638224 | 0.80 | TDP1 (0.55) | TDP1KDM4EMAPK1RECQLMAPT | |
| SCHEMBL19771234 | 0.79 | TDP1 (0.70) | TDP1KDM4EMAPK1RECQLMAPT | |
| SCHEMBL19771233 | 0.79 | TDP1 (0.70) | TDP1KDM4EMAPK1RECQLMAPT | |
| SCHEMBL29102057 | 0.79 | TDP1 (0.68) | TDP1KDM4EMAPK1RECQLMAPT | |
| SCHEMBL7845490 | 0.78 | TDP1 (0.53) | TDP1KDM4EMAPK1RECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4695580-A | Phenylserine derivatives and processes for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1987-09-22 | — | — | US | disclosed |