SCHEMBL7845490

SCHEMBL7845490

NC(CO)c1ccc(O)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 11/20 0.53
KDM4E B2RXH2 9/20 0.53
RECQL P46063 8/20 0.53
MAPT P10636 8/20 0.53
BLM P54132 6/20 0.53
LMNA P02545 5/20 0.53
APEX1 P27695 4/20 0.53
KMT2A Q03164 4/20 0.53
MAPK1 P28482 4/20 0.53
ADRA1A P35348 3/20 0.53
MEN1 O00255 3/20 0.53
HPGD P15428 2/20 0.53
ADRB2 P07550 2/20 0.53
ADRB1 P08588 2/20 0.53
ADRA2A P08913 2/20 0.53
ADORA3 P0DMS8 2/20 0.53
ADRB3 P13945 2/20 0.53
DRD2 P14416 2/20 0.53
ADRA2B P18089 2/20 0.53
ADRA2C P18825 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9073372 0.83 CA2 (0.47) TDP1KDM4ERECQLMAPTBLM
SCHEMBL10804202 0.82 TDP1 (0.36) TDP1KDM4ERECQLMAPTBLM
SCHEMBL11430514 0.81 TDP1 (0.62) TDP1KDM4ERECQLMAPTBLM
SCHEMBL13479446 0.81 TDP1 (0.62) TDP1KDM4ERECQLMAPTBLM
SCHEMBL14303527 0.81 TDP1 (0.62) TDP1KDM4ERECQLMAPTBLM
SCHEMBL1444985 0.78 ANPEP (0.41) TDP1KDM4EAPEX1TAAR1TSHR
SCHEMBL11422792 0.78 TDP1 (0.54) TDP1KDM4ERECQLMAPTBLM
SCHEMBL10802005 0.78 TDP1 (0.69) TDP1KDM4ERECQLMAPTBLM
SCHEMBL8372401 0.77 TSHR (0.68) BLMLMNAMAPK1CYP3A4TAAR1
SCHEMBL4965778 0.76 TDP1 (0.54) TDP1KDM4ERECQLMAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000032167-A9 A POLYSOME SDG INC (US) 2001-12-13 WO claimed
WO-2000032167-A1 A POLYSOME SDG, INC. (US) 2000-06-08 WO claimed
EP-1005327-A1 TARGETED LIPOSOMAL CONSTRUCTS FOR DIAGNOSTIC AND THERAPEUTIC USES SDG, INC. (US) 2000-06-07 EP claimed
EP-0999855-A1 POLYMER BASED PHARMACEUTICAL COMPOSITIONS FOR TARGETED DELIVERY OF BIOLOGICALLY ACTIVE AGENTS SDG, Inc. (US) 2000-05-17 EP claimed
WO-1999004824-A1 POLYMER BASED PHARMACEUTICAL COMPOSITIONS FOR TARGETED DELIVERY OF BIOLOGICALLY ACTIVE AGENTS SDG, INC. (US) 1999-02-04 WO claimed
WO-1999001110-A1 TARGETED LIPOSOMAL CONSTRUCTS FOR DIAGNOSTIC AND THERAPEUTIC USES SDG, INC. (US) 1999-01-14 WO claimed
EP-0341808-B2 Process for coloring hair with aminoalkyl or aminohydroxyalkyl catechol compositions BRISTOL MYERS SQUIBB CO (US) 1996-12-18 EP claimed
US-4904274-A Coloring hair with aminoalkyl-or aminohydroxyalkyl-catechols CLAIROL INCORPORATED (US) 1990-02-27 US claimed
EP-0341808-A1 Process for coloring hair with aminoalkyl or aminohydroxyalkyl catechol compositions Bristol-Myers Squibb Company (US) 1989-11-15 EP claimed
CN-117229533-A Anti-freezing hydrogel based on extracted grape residues and preparation method and application thereof 鲁东大学 2023-12-15 CN disclosed
WO-2000032167-A9 A POLYSOME SDG INC (US) 2001-12-13 WO disclosed
EP-1007068-A4 PROCESS FOR PREPARING SYNTHETIC SOIL-EXTRACT MATERIALS AND MEDICAMENTS BASED THEREON LAUB BIOCHEMICALS CORP (US) 2001-04-25 EP disclosed
EP-1007068-A1 PROCESS FOR PREPARING SYNTHETIC SOIL-EXTRACT MATERIALS AND MEDICAMENTS BASED THEREON Laub Biochemicals Corporation (US) 2000-06-14 EP disclosed
WO-2000032167-A1 A POLYSOME SDG, INC. (US) 2000-06-08 WO disclosed
US-5081033-A Effective amount of ammonium ions to enhance chlamydospore por duction by strains of Candida albicans WADLEY TECHNOLOGIES, INC. (US) 1992-01-14 US disclosed
US-4847128-A INCUBATION, ANALYZING WADLEY TECHNOLOGIES, INC. (US) 1989-07-11 US disclosed
EP-0160743-B1 MINIATURIZED YEAST IDENTIFICATION SYSTEM Wadley Technologies, Inc. (US) 1989-03-22 EP disclosed
US-4728607-A CULTURE CONTAINER FOR VIEWING UNDER MICROSCOPE J. K. AND SUSIE L. WADLEY RESEARCH INSTITUTE AND BLOOD BANK (US) 1988-03-01 US disclosed
EP-0160743-A2 Miniaturized yeast identification system Wadley Technologies, Inc. (US) 1985-11-13 EP disclosed
US-4144133-A OXGALL, SAPONIN, SUBSTRATE FOR PHENOL OXIDASE J. K. AND SUSIE L. WADLEY RESEARCH INSTITUTE AND BLOOD BANK (US) 1979-03-13 US disclosed