⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10800470 | 0.95 | — | — | |
| SCHEMBL10819114 | 0.93 | — | — | |
| SCHEMBL10805163 | 0.89 | — | — | |
| SCHEMBL10800553 | 0.85 | — | — | |
| SCHEMBL10817914 | 0.84 | KCNK3 (0.70) | — | |
| SCHEMBL10804832 | 0.84 | KCNK3 (0.61) | — | |
| SCHEMBL10806622 | 0.82 | — | — | |
| SCHEMBL10805647 | 0.81 | KCNK3 (0.68) | — | |
| SCHEMBL10800970 | 0.81 | KCNK3 (0.67) | — | |
| SCHEMBL10805706 | 0.80 | KCNK3 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086422-B1 | PHARMACOLOGICALLY ACTIVE PYRAZOLO(4,3-C)PYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1987-09-30 | — | — | EP | disclosed |