Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 8/20 | 0.67 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10805647 | 0.99 | KCNK3 (0.68) | KCNK3 | |
| SCHEMBL10799561 | 0.85 | KCNK3 (0.67) | KCNK3 | |
| SCHEMBL10800470 | 0.85 | — | — | |
| SCHEMBL10801107 | 0.83 | KCNK3 (0.86) | KCNK3CTSS | |
| SCHEMBL10801148 | 0.83 | KCNK3 (0.69) | KCNK3 | |
| SCHEMBL14784434 | 0.80 | KCNK3 (0.80) | KCNK3 | |
| SCHEMBL14791429 | 0.80 | KCNK3 (1.00) | KCNK3 | |
| SCHEMBL10803377 | 0.80 | — | — | |
| SCHEMBL10801167 | 0.80 | KCNK3 (0.81) | KCNK3CTSS | |
| SCHEMBL2986353 | 0.79 | CTSS (0.67) | KCNK3CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086422-B1 | PHARMACOLOGICALLY ACTIVE PYRAZOLO(4,3-C)PYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1987-09-30 | — | — | EP | disclosed |