Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Cinnamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.79 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.79 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.79 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.79 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.79 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.79 |
| ▸ | TNKS | O95271 | 1/20 | 0.79 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.79 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.79 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.79 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.79 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.79 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.79 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamic Acid SCHEMBL10996900 | 1.00 | HCAR2 (0.79) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL11878212 | 0.98 | HCAR2 (0.76) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL11878207 | 0.98 | HCAR2 (0.76) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL653828 | 0.89 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL1332 | 0.89 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL29989544 | 0.89 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL1706935 | 0.89 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL3406486 | 0.89 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL653827 | 0.89 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL50466 | 0.89 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041574-B | Catalyst component for olefin polymerization and application thereof | 中国石油化工股份有限公司 | 2024-08-20 | — | — | CN | claimed |
| CN-114478846-B | Carrier of catalyst with olefin polymerization catalyzing function, preparation method and application thereof, olefin polymerization catalyst and application thereof | 中国石油化工股份有限公司 | 2023-09-08 | — | — | CN | claimed |
| US-11141412-B2 | Analogs of pridopidine, their preparation and use | PRILENIA NEUROTHERAPEUTICS LTD. (IL) | 2021-10-12 | — | — | US | claimed |
| CN-119317422-A | Cosmetic composition comprising natural resin | 莱雅公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119032181-A | Modified sophorolipids for improving the bioavailability of amino acids and methods of use | 轨迹方案IPCO有限责任公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-116023548-B | External electron donor composition, application thereof, catalyst system and olefin polymerization method | 中国石油化工股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-116023555-B | External electron donor, application thereof, catalyst system for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-114437264-B | Low-VOC low-odor polypropylene resin and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-114478870-B | Catalyst system for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-114507303-B | External electron donor for olefin polymerization, catalyst system and olefin polymerization method | 中国石油化工股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-116041576-A | Olefin polymerization catalyst precursor, olefin polymerization catalyst carrier, preparation method and application thereof | 中国石油化工股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-116023549-A | Prepolymerized catalyst, preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-116023547-A | Catalyst component, catalyst and method for olefin polymerization | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-116023555-A | External electron donor, application thereof, catalyst system for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-116023527-A | Slurry catalyst and paste catalyst, and preparation methods and applications thereof | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| US-20160287536-A1 | Composition | THE UNIVERSITY OF NOTTINGHAM (GB) | 2016-10-06 | — | — | US | disclosed |
| EP-3071186-A2 | COMPOSITION | The University Of Nottingham (GB) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015075464-A2 | COMPOSITION | THE UNIVERSITY OF NOTTINGHAM (GB) | 2015-05-28 | — | — | WO | disclosed |
| US-4715933-A | HIGH BOILING HYDROCARBON OXIDATE AS EXTRACTANT | BERG LLOYD (US) | 1987-12-29 | — | — | US | disclosed |
| US-4554360-A | DIARYLIODONIUM SALT, IODOARENE, COUPLING | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1985-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11141412-B2 | Analogs of pridopidine, their preparation and use | PDE7A, PDE3A, PDE4D | DPP4 1245/4885HCAR2 1728/4885HDAC3 2044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.