Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 7/20 | 0.44 |
| ▸ | THRB | P10828 | 6/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10807087 | 0.95 | THRA (0.43) | THRATHRBHRH3S1PR4S1PR1 | |
| SCHEMBL10808906 | 0.93 | THRA (0.44) | THRATHRBHRH3S1PR4S1PR1 | |
| SCHEMBL10810128 | 0.91 | THRA (0.45) | THRATHRBS1PR4S1PR1S1PR3 | |
| SCHEMBL10804074 | 0.90 | THRA (0.46) | THRATHRB | |
| SCHEMBL10809712 | 0.90 | THRA (0.46) | THRATHRB | |
| SCHEMBL10807570 | 0.90 | THRA (0.42) | THRATHRBHRH3S1PR4S1PR1 | |
| SCHEMBL10806773 | 0.90 | THRA (0.42) | THRATHRBHRH3S1PR4S1PR1 | |
| SCHEMBL10808022 | 0.89 | CYP2D6 (0.46) | THRATHRB | |
| SCHEMBL10810038 | 0.88 | THRA (0.43) | THRATHRBHRH3S1PR4S1PR1 | |
| SCHEMBL10802619 | 0.87 | S1PR1 (0.41) | S1PR4S1PR1S1PR3S1PR5PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4640913-A | Phosphocholine derivatives having antihypertensive action | AMERICAN CYANAMID COMPANY (US) | 1987-02-03 | — | — | US | disclosed |