Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10806823 | 1.00 | PPARA (0.47) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10808654 | 0.96 | PPARA (0.46) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10811983 | 0.96 | PPARA (0.46) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10805747 | 0.95 | PPARA (0.45) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10808531 | 0.95 | PPARA (0.45) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10807777 | 0.92 | PPARA (0.46) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10805731 | 0.92 | PPARA (0.46) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10805717 | 0.91 | PPARA (0.46) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10810263 | 0.91 | PPARA (0.46) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL9652630 | 0.89 | PPARA (0.48) | PPARAPPARGCNR1CNR2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4640913-A | Phosphocholine derivatives having antihypertensive action | AMERICAN CYANAMID COMPANY (US) | 1987-02-03 | — | — | US | disclosed |