Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10806823 | 0.89 | PPARA (0.47) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10804840 | 0.89 | PPARA (0.47) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10808654 | 0.88 | PPARA (0.46) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10811983 | 0.88 | PPARA (0.46) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10805747 | 0.88 | PPARA (0.45) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10808531 | 0.88 | PPARA (0.45) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10809673 | 0.85 | PPARA (0.47) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10807017 | 0.85 | PPARA (0.47) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10810673 | 0.85 | PPARA (0.46) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL10813119 | 0.85 | PPARA (0.46) | PPARAPPARGCNR1CNR2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4894367-A | CARDIOVASCULAR DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1990-01-16 | — | — | US | claimed |
| US-5126291-A | Non-steroidal antiinflammatory agents | AMERICAN CYANAMID COMPANY (US) | 1992-06-30 | — | — | US | disclosed |
| US-4981989-A | Antihypertensive phosphate derivatives and intermediates thereof | AMERICAN CYANAMID COMPANY (US) | 1991-01-01 | — | — | US | disclosed |
| US-4894367-A | CARDIOVASCULAR DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1990-01-16 | — | — | US | disclosed |
| US-4883816-A | SULFONYL DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4762942-A | AMINO SUBSTITUTED, INNER SALTS | AMERICAN CYANAMID CO. (US) | 1988-08-09 | — | — | US | disclosed |