Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | THRB | P10828 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | APEX1 | P27695 | 2/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124164 | 0.85 | MAOA (0.79) | MAOAMAOBADORA2AALDH1A1MEN1 | |
| SCHEMBL27480075 | 0.84 | MAOA (0.70) | MAOAMAOBADORA2AALDH1A1MEN1 | |
| SCHEMBL28287512 | 0.82 | MAOA (0.68) | MAOAMAOBADORA2AALDH1A1MEN1 | |
| SCHEMBL10733345 | 0.81 | MEN1 (0.56) | MAOAMAOBADORA2AALDH1A1MEN1 | |
| SCHEMBL10356104 | 0.79 | ADORA2A (0.73) | MAOAADORA2AALDH1A1MEN1KMT2A | |
| SCHEMBL11363165 | 0.79 | ADORA2A (0.73) | MAOAADORA2AALDH1A1MEN1KMT2A | |
| SCHEMBL10355771 | 0.79 | ADORA2A (0.73) | MAOAADORA2AALDH1A1MEN1KMT2A | |
| SCHEMBL10355835 | 0.79 | ADORA2A (0.73) | MAOAADORA2AALDH1A1MEN1KMT2A | |
| SCHEMBL11173886 | 0.79 | ADORA2A (0.73) | MAOAADORA2AALDH1A1MEN1KMT2A | |
| SCHEMBL10355814 | 0.78 | ADORA2A (0.77) | MAOAMAOBADORA2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103381-B1 | SUBSTITUTED ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONES | WARNER-LAMBERT COMPANY (US) | 1987-09-23 | — | — | EP | disclosed |
| US-4556654-A | ANTICARCINOGENIC, FUNGICIDES, ANTISEPTICS | WARNER-LAMBERT COMPANY (US) | 1985-12-03 | — | — | US | disclosed |
| EP-0103381-A1 | Substituted anthra(1,9-cd)pyrazol-6(2H)-ones | WARNER-LAMBERT COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |