Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.56 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | GLA | P06280 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.55 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30853545 | 0.98 | ALDH1A1 (0.58) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL29712310 | 0.98 | ALDH1A1 (0.58) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL297515 | 0.98 | ALDH1A1 (0.58) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL17099903 | 0.96 | ALDH1A1 (0.56) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL27526630 | 0.94 | HPRT1 (0.56) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL4299906 | 0.89 | ALDH1A1 (0.70) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL6256852 | 0.87 | ALDH1A1 (0.47) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL30373734 | 0.87 | ALDH1A1 (0.60) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL604812 | 0.87 | ALDH1A1 (0.60) | ALDH1A1GLAHPGDMAPTACHE | |
| Phenanthrene SCHEMBL27653554 | 0.87 | ALDH1A1 (0.75) | ALDH1A1GLAHPGDMAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647518-A | Light-emitting display component and method for light-emitting display using the same | CANON KABUSHIKI KAISHA (JP) | 1987-03-03 | — | — | US | disclosed |