Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trestolone Acetate SCHEMBL2787569 | 0.86 | AR (0.70) | ARMAPTLMNASERPINA6ALDH1A1 | |
| Trestolone Acetate SCHEMBL12101463 | 0.86 | AR (0.70) | ARMAPTLMNASERPINA6ALDH1A1 | |
| Trestolone Acetate SCHEMBL17302814 | 0.86 | AR (0.70) | ARMAPTLMNASERPINA6ALDH1A1 | |
| Trestolone Acetate SCHEMBL25863451 | 0.86 | AR (0.70) | ARMAPTLMNASERPINA6ALDH1A1 | |
| Trestolone Acetate SCHEMBL7779251 | 0.86 | AR (0.70) | ARMAPTLMNASERPINA6ALDH1A1 | |
| Trestolone Acetate SCHEMBL17302787 | 0.86 | AR (0.70) | ARMAPTLMNASERPINA6ALDH1A1 | |
| Trestolone Acetate SCHEMBL17302820 | 0.86 | AR (0.70) | ARMAPTLMNASERPINA6ALDH1A1 | |
| SCHEMBL29462890 | 0.84 | AR (0.72) | ARMAPTLMNASERPINA6ALDH1A1 | |
| SCHEMBL6836733 | 0.83 | MAPT (0.57) | ARMAPTLMNASERPINA6ALDH1A1 | |
| SCHEMBL6848899 | 0.83 | AR (0.55) | ARMAPTLMNASERPINA6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659516-A | ANTIESTROGENS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0138504-A2 | Steroid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-04-24 | — | — | EP | disclosed |