Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | GYPA | P02724 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | HRAS | P01112 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10755807 | 1.00 | PDE4D (0.51) | PDE4DSLC6A2LGALS8PSEN1PSEN2 | |
| SCHEMBL10755806 | 1.00 | PDE4D (0.51) | PDE4DSLC6A2LGALS8PSEN1PSEN2 | |
| SCHEMBL1776370 | 1.00 | PDE4D (0.51) | PDE4DSLC6A2LGALS8PSEN1PSEN2 | |
| SCHEMBL1776369 | 1.00 | PDE4D (0.51) | PDE4DSLC6A2LGALS8PSEN1PSEN2 | |
| SCHEMBL10807993 | 0.91 | PDE4D (0.54) | PDE4DSLC6A2LGALS8PSEN1PSEN2 | |
| SCHEMBL19891704 | 0.88 | PDE4D (0.49) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL7909402 | 0.84 | PDE4D (0.42) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL10904817 | 0.84 | PDE4D (0.55) | PDE4DSLC6A2TSHRCYP2C19ADORA2A | |
| SCHEMBL6451122 | 0.84 | PDE4D (0.55) | PDE4DSLC6A2TSHRCYP2C19ADORA2A | |
| SCHEMBL10904820 | 0.84 | PDE4D (0.55) | PDE4DSLC6A2TSHRCYP2C19ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943584-B2 | Medicinal composition containing diabetes remedy | SANKYO COMPANY, LIMITED (JP) | 2011-05-17 | — | — | US | disclosed |
| EP-1589023-B1 | OLIGOSACCHARIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | disclosed |
| US-7632930-B2 | Oligosaccharide derivative | SANKYO COMPANY LIMITED (JP) | 2009-12-15 | — | — | US | disclosed |
| US-20080194495-A1 | Oligosaccharide Derivative | HONDA TAKESHI | 2008-08-14 | — | — | US | disclosed |
| US-7361744-B2 | Oligosaccharide derivative | SANKYO COMPANY LIMITED (JP) | 2008-04-22 | — | — | US | disclosed |
| US-20080039367-A1 | Medicinal Composition Containing Diabeted Remedy | SANKYO COMPANY, LIMITED (JP) | 2008-02-14 | — | — | US | disclosed |
| EP-1792620-A1 | MEDICINAL COMPOSITION CONTAINING DIABETES REMEDY | Sankyo Company, Limited (JP) | 2007-06-06 | — | — | EP | disclosed |
| US-20060025350-A1 | Oligosaccharide derivative | SANKYO COMPANY, LIMITED (JP) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039367-A1 | Medicinal Composition Containing Diabeted Remedy | DPP4, IAPP, AMY2A | PDE4D 105/4885SLC6A2 2459/4885LGALS8 651/4885 |
| US-20060025350-A1 | Oligosaccharide derivative | MAN1B1, FUT6, MAN2A1 | PDE4D 1699/4885SLC6A2 4529/4885LGALS8 171/4885 |
| US-20080194495-A1 | Oligosaccharide Derivative | MAN1B1, FUT6, MAN2A1 | PDE4D 1699/4885SLC6A2 4529/4885LGALS8 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.