Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10807845 | 0.80 | KDM4E (0.47) | KDM4EPPARGPPARAPPARDNPSR1 | |
| SCHEMBL10810604 | 0.79 | PPARG (0.46) | KDM4EPPARGPPARAPPARDNPSR1 | |
| SCHEMBL10810978 | 0.68 | KDM4E (0.44) | KDM4E | |
| SCHEMBL10815045 | 0.68 | KDM4E (0.46) | KDM4EPPARGPPARAGABRR1 | |
| SCHEMBL10815049 | 0.68 | KDM4E (0.46) | KDM4EPPARGPPARAGABRR1 | |
| SCHEMBL17046737 | 0.66 | NTRK1 (0.35) | KDM4ENTRK1 | |
| SCHEMBL13765709 | 0.66 | KDM4E (0.57) | KDM4EPPARGPPARAALDH1A1POLB | |
| SCHEMBL21678960 | 0.65 | HCRTR2 (0.39) | KDM4EPPARGPPARAPPARDALDH1A1 | |
| SCHEMBL4675656 | 0.64 | KDM4E (0.51) | KDM4EPPARGPPARAGABRR1GAA | |
| SCHEMBL21679257 | 0.64 | SMN1; SMN2 (0.36) | KDM4EPPARGPPARAPPARDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096890-B1 | OXAZOLEACETIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND COMPOSITIONS CONTAINING SAID DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1987-11-25 | — | — | EP | claimed |
| US-4602027-A | HYPOGLYCEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-22 | — | — | US | claimed |
| EP-0096890-A2 | Oxazoleacetic acid derivatives, process for their production and compositions containing said derivatives | Takeda Chemical Industries, Ltd. (JP) | 1983-12-28 | — | — | EP | claimed |
| EP-0096890-B1 | OXAZOLEACETIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND COMPOSITIONS CONTAINING SAID DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1987-11-25 | — | — | EP | disclosed |
| US-4602027-A | HYPOGLYCEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-22 | — | — | US | disclosed |
| EP-0096890-A2 | Oxazoleacetic acid derivatives, process for their production and compositions containing said derivatives | Takeda Chemical Industries, Ltd. (JP) | 1983-12-28 | — | — | EP | disclosed |