Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 9/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.53 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10806716 | 1.00 | S1PR1 (0.54) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL10813470 | 0.95 | S1PR1 (0.53) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL10810853 | 0.95 | S1PR1 (0.53) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL10806442 | 0.90 | S1PR1 (0.51) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL10813542 | 0.90 | S1PR1 (0.51) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL10805739 | 0.88 | PPARA (0.47) | — | |
| SCHEMBL10808732 | 0.86 | S1PR1 (0.51) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL10807984 | 0.86 | S1PR1 (0.51) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL10817789 | 0.83 | PPARA (0.49) | S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL10806131 | 0.82 | CETP (0.40) | MEN1ALDH1A1LMNAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4640913-A | Phosphocholine derivatives having antihypertensive action | AMERICAN CYANAMID COMPANY (US) | 1987-02-03 | — | — | US | disclosed |