Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10808732 | 1.00 | S1PR1 (0.51) | S1PR1S1PR4S1PR5S1PR3S1PR2 | |
| SCHEMBL10806442 | 0.96 | S1PR1 (0.51) | S1PR1S1PR4S1PR5S1PR3S1PR2 | |
| SCHEMBL10813542 | 0.96 | S1PR1 (0.51) | S1PR1S1PR4S1PR5S1PR3S1PR2 | |
| SCHEMBL10810853 | 0.91 | S1PR1 (0.53) | S1PR1S1PR4S1PR5S1PR3S1PR2 | |
| SCHEMBL10813470 | 0.91 | S1PR1 (0.53) | S1PR1S1PR4S1PR5S1PR3S1PR2 | |
| SCHEMBL10804674 | 0.89 | PPARA (0.47) | S1PR1S1PR4S1PR5S1PR3ADRA1D | |
| SCHEMBL10809825 | 0.86 | S1PR1 (0.54) | S1PR1S1PR4S1PR5S1PR3S1PR2 | |
| SCHEMBL10806716 | 0.86 | S1PR1 (0.54) | S1PR1S1PR4S1PR5S1PR3S1PR2 | |
| SCHEMBL10805976 | 0.85 | PPARA (0.47) | S1PR1S1PR4S1PR5S1PR3ADRA1D | |
| SCHEMBL10810938 | 0.83 | ADRA1D (0.45) | ADRA1DPTAFRHTR1DHTR2CADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4640913-A | Phosphocholine derivatives having antihypertensive action | AMERICAN CYANAMID COMPANY (US) | 1987-02-03 | — | — | US | disclosed |