Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 12/20 | 0.47 |
| ▸ | THRB | P10828 | 11/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10808557 | 1.00 | THRA (0.47) | THRATHRBESR1CNR2ITGB3 | |
| SCHEMBL10805761 | 0.94 | THRA (0.46) | THRATHRBESR1ITGB3ITGA2B | |
| SCHEMBL10808155 | 0.94 | THRA (0.46) | THRATHRBESR1ITGB3ITGA2B | |
| SCHEMBL10810128 | 0.91 | THRA (0.45) | THRATHRBESR1CNR2 | |
| SCHEMBL10809712 | 0.90 | THRA (0.46) | THRATHRBESR1 | |
| SCHEMBL10804074 | 0.90 | THRA (0.46) | THRATHRBESR1 | |
| SCHEMBL10810610 | 0.90 | THRA (0.44) | THRATHRBCNR2 | |
| SCHEMBL10808324 | 0.90 | THRA (0.45) | THRATHRBITGB3ITGA2B | |
| SCHEMBL10811338 | 0.90 | THRA (0.45) | THRATHRBITGB3ITGA2B | |
| SCHEMBL10810100 | 0.89 | THRA (0.48) | THRATHRBCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4640913-A | Phosphocholine derivatives having antihypertensive action | AMERICAN CYANAMID COMPANY (US) | 1987-02-03 | — | — | US | disclosed |