Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 7/20 | 0.43 |
| ▸ | THRB | P10828 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10808826 | 1.00 | THRA (0.43) | THRATHRBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10811408 | 0.98 | THRA (0.43) | THRATHRBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10808193 | 0.98 | THRA (0.43) | THRATHRBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10806555 | 0.95 | THRA (0.43) | THRATHRB | |
| SCHEMBL10807951 | 0.95 | THRA (0.43) | THRATHRB | |
| SCHEMBL10811673 | 0.89 | THRA (0.44) | THRATHRBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10804868 | 0.89 | S1PR1 (0.40) | THRATHRBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10807718 | 0.89 | S1PR1 (0.40) | THRATHRBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10809383 | 0.87 | THRA (0.44) | THRATHRBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10808608 | 0.86 | S1PR1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4640913-A | Phosphocholine derivatives having antihypertensive action | AMERICAN CYANAMID COMPANY (US) | 1987-02-03 | — | — | US | disclosed |