Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025789 | 1.00 | ATM (0.31) | ATMMAPT | |
| SCHEMBL13677158 | 0.85 | ATM (0.41) | ATM | |
| SCHEMBL27156699 | 0.85 | ATM (0.41) | ATM | |
| SCHEMBL19084014 | 0.85 | ATM (0.41) | ATM | |
| SCHEMBL19083748 | 0.80 | PIK3CD (0.40) | MAPT | |
| SCHEMBL19083750 | 0.80 | TSHR (0.37) | MAPT | |
| SCHEMBL19075601 | 0.80 | RIPK1 (0.46) | — | |
| SCHEMBL627415 | 0.77 | HSD17B10 (0.47) | — | |
| Ethane SCHEMBL4767713 | 0.77 | HSD17B10 (0.47) | — | |
| SCHEMBL6078598 | 0.77 | HSD17B10 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448946-A1 | 2-CARBOXAMIDE CYCLOAMINO UREAS USEFUL AS PI3K INHIBITORS | Novartis AG (CH) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011000855-A1 | 2-CARBOXAMIDE CYCLOAMINO UREAS USEFUL AS PI3K INHIBITORS | NOVARTIS AG (CH) | 2011-01-06 | — | — | WO | disclosed |